TAILORED ANTICOAGULANT TREATMENT AFTER A FIRST VENOUS THROMBOEMBOLISM: PROTOCOL OF THE LEIDEN THROMBOSIS RECURRENCE RISK PREVENTION (L-TRRIP) STUDY - COHORT-BASED RANDOMISED CONTROLLED TRIAL

Tailored anticoagulant treatment after a first venous thromboembolism: protocol of the Leiden Thrombosis Recurrence Risk Prevention (L-TRRiP) study - cohort-based randomised controlled trial

Introduction Patients with a first venous thromboembolism (VTE) are at risk of recurrence.Recurrent VTE (rVTE) can be prevented by extended anticoagulant therapy, but this comes at the cost of an increased risk of bleeding.It is still uncertain whether patients with an intermediate recurrence risk or with a high recurrence and high bleeding risk wi

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3D reconstruction method based on second-order semiglobal stereo matching and fast point positioning Delaunay triangulation

Binocular vision uses the parallax principle of the human eye to obtain 3D information of an object, which is Frame Light Box widely used as an important means of acquiring 3D information for 3D reconstruction tasks.To improve the accuracy and efficiency of 3D reconstruction, we propose a 3D reconstruction method that combines second-order semiglob

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A MTA2-SATB2 chromatin complex restrains colonic plasticity toward small intestine by retaining HNF4A at colonic chromatin

Abstract Plasticity among cell lineages is a fundamental, but poorly understood, property of regenerative tissues.In the gut tube, the small intestine absorbs nutrients, whereas the colon absorbs electrolytes.In a striking display of inherent plasticity, adult colonic mucosa lacking the chromatin factor SATB2 is converted to small intestine.Using p

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